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  >>Assay Development and Detection                                                                                                   
                                                                              
  Can Get Signal Immunoreaction Signal Enhancer
      "ImmunoReaction" - for blotting and ELISA applications
"ImmunoStain" - for tissue staining applications
 
 

IMMUNO SHOT - immuno-reaction enhancing solution.
Histofine® Polymer Detection Kits for IHC - techonologically advanced, sensitive, convenient.
arrow Ab-Capcher™, Ab-Rapid-PuRe™, Ab-Rapid-SPiN™alkalai tolerant, high capacity Protein A
IMMUTEX™ polystyrene latex particles- for in-vitro diagnostic assay development
d Magnosphere™ high performance paramagnetic microparticles
2-D Silver Stain II Reagent Set - for protein or nucleic acid detection following electrophoresis.
Blocking Solution - for low background immunoassays. Animal free, polymer-based.
Enzyme Stablizer - for Peroxidase and Phosphatase conjugates. Animal free, polymer based.
Multipurpose Incubation Chamber - for slide-based applications.
Fluolid Fluorescent Dyes - conjugation kits for oligos and proteins
Super PAP Pen Mini - draws hydrophobic barriers on microscope slides.
arrow Tissue Capture Pen - improves section attachement to IHC and ICC slides.
Tube Checker Pen - solvent-proof permenant marking pen
Hybri-Bag - Heat-sealable bags.
Easy-WESTERN II - high sensitivity primary antibody detection in western blotting
Antibodies to Immunoglobulins
Luciferase FM Assays - -ideally suited for high sensitivity ATP detection


 

  Can Get Signal ImmunoReaction Enhancer Solution  
Simply use Can Get Signal solution as antibody diluent for Westerns, ELISAs, dot blots, etc. Can Get Signal dramtically increase s/n ratios in many systems. Compatible with colorimetric, chemiluminescent, and fluorescent detection methods. Enzyme labeled antibodies are not disturbed. Enhancer Sets inclue include one solution optimized for primary (1°) abs and one solution optimized for secondary (2°) abs.
 
   
Improved detection of phosphorylated Akt. (Insulin stimulated bovine cells)
Item
Cat. No
Quantity
Price
Can Get Signal Immunoreaction Enhancer Solution Set pdf
TYB-NKB-101
2 x 250 ml
$ 502
Can Get Signal Immunoreaction Enhancer Solution Set pdf
TYB-NKB-101T
2 x 50 ml
$ 168
Can Get Signal Immunoreaction Enhancer Solution For Primary Antibody pdf
TYB-NKB-201
250 ml
$ 284
Can Get Signal Immunoreaction Enhancer Solution For Secondary Antibody pdf
TYB-NKB-301
250 ml
$ 284


 

  Can Get Signal Immunostain Enhancer Solution  
Optimized for cell staining, Can Get Immunostain Enhancer increases s/n ratio and decreases non-specific background. Fully compatible with enzyme and fluorescent linked antibodies. Use on paraffin embedded or frozen sections. Compare Solution A to Solution B in Starter Set to find which works best in your systems.
 
   
1 second exposure using Solution A
Item
Cat. No
Quantity
Price
Can Get Signal immunostain Solution Starter Set pdf
TYB-NKB-401
2 x 5 ml
$ 202
Can Get Signal immunostain Solution A pdf
TYB-NKB-501
1 x 20 ml
$ 502
Can Get Signal immunostain Solution A pdf
TYB-NKB-502
4 x 20 ml
discontinued
Can Get Signal immunostain Solution B pdf
TYB-NKB-601
1 x 20 ml
$ 502
Can Get Signal immunostain Solution B pdf
TYB-NKB-602
4 x 20 ml
discontinued




IMMUNO SHOT  

IMMUNO SHOT an enhancer of antigen-antibody reaction. Ready to use antibody diluent for Western blots, ELISAs, and other antibody reactions. Compatible with HRP or AP conjugated antibodies.

   
   
Item
Cat. No
Quantity
Price
IMMUNO SHOT Reagent 1&2
CSR-IS-012-100
kit
$ 123
IMMUNO SHOT Reagent 1&2
CSR-IS-012-250
kit
$ 225
IMMUNO SHOT Reagent 1
CSR-IS-001-100
100ml
$ n/a
IMMUNO SHOT Reagent 1
CSR-IS-001-250
250ml
$ 119
IMMUNO SHOT Reagent 2
CSR-IS-002-100
100ml
$ n/a
IMMUNO SHOT Reagent 2
CSR-IS-002-250
250ml
$ 119



N-Histofine® Polymer Detection Systems for IHC Staining  

N-Histofine® Staining systems- easy to use enzyme-conjugated secondary antibody in one step
Simplified staining protocol eliminates two steps: pre-blocking and incubation with streptavidin-enzyme conjugate.  Signal amplification increases sensitivity. Undetected endogenous biotin decreases background. Available for Human, Mouse and Rat tissue sections.

   
   
Item
Cat. No
Quantity
Price
N-Histofine® for MOUSE TISSUE
N-Histofine(R) Mousestain Kit
for HRP staining of mouse tissue with mouse 1° antibody
NIC-414321F
50 slides
1 x 6ml
$618
N-Histofine(R) Mousestain Kit
for HRP staining of mouse tissue with mouse 1° antibody
NIC-414322F
500 slides
3 x 17ml
$992
N-Histofine(R) Simple Stain Mouse MAX PO (R)
for HRP staining of mouse tissue with rabbit 1° antibody
NIC-414341F
170 slides
1 x 17ml
$420
N-Histofine(R) Simple Stain Mouse MAX PO (G)
for HRP staining of mouse tissue with goat 1° antibody
NIC-414351F
170 slides
1 x 17ml
$420
N-Histofine(R) Simple Stain Mouse MAX PO (Rat)
for HRP staining of mouse tissue with rat 1° antibody
NIC-414311F
170 slides
1 x 17ml
$420
N-Histofine® for RAT TISSUE
N-Histofine(R) Simple Stain Rat MAX PO (MULTI)
for HRP staining of rat tissue with mouse or rabbit 1° antibody
NIC-414191F
170 slides
1 x 17ml
$387
N-Histofine(R) Simple Stain Rat MAX PO (M)
for HRP staining of rat tissue with mouse 1° antibody
NIC-414171F
170 slides
1 x 17ml
$387
N-Histofine(R) Simple Stain Rat MAX PO (R)
for HRP staining of rat tissue with rabbit 1° antibody
NIC-414181F
170 slides
1 x 17ml
$387
N-Histofine(R) Simple Stain Rat MAX PO (G)
for HRP staining of rat tissue with goat 1° antibody
NIC-414331F
170 slides
1 x 17ml
$387
N-Histofine® for HUMAN TISSUE
N-Histofine(R) Simple Stain MAX PO (MULTI)
for HRP staining of human tissue with mouse or rabbit 1° antibody
NIC-414151F
170 slides
1 x 17ml
$364
N-Histofine(R) Simple Stain MAX PO (MULTI)
for HRP staining of human tissue with mouse or rabbit 1° antibody
NIC-414152F
500 slides
2 x 17ml
$530
N-Histofine® Simple Stain MAX PO (MULTI)
for HRP staining of human tissue with mouse or rbt 1° antibody
NIC-414154F
1500 slides
3 x 17ml
$1104
N-Histofine(R) Simple Stain MAX PO (M)
for HRP staining of human tissue with mouse primary antibody
NIC-414131F
170 slides
1 x 17ml
$331
N-Histofine(R) Simple Stain MAX PO (M)
for HRP staining of human tissue with mouse primary antibody
NIC-414132F
500 slides
2 x 17ml
$496
N-Histofine(R) Simple Stain MAX PO (M)
for HRP staining of human tissue with mouse primary antibody
NIC-414134F
1500 slides
3 x 17ml
$1082
N-Histofine(R) Simple Stain MAX PO (R)
for HRP staining of human tissue with rabbit primary antibody
NIC-414141F
170 slides
1 x 17ml
$331
NIC-414142F
500 slides
2 x 17ml
$496
N-Histofine(R) Simple Stain MAX PO (R)
for HRP staining of human tissue with rabbit primary antibody
NIC-414144F
1500 slides
3 x 17ml
$1082
N-Histofine(R) Simple Stain MAX PO (G)
for HRP staining of human tissue with goat primary antibody
NIC-414161F
170 slides
1 x 17ml
$331
N-Histofine(R) Simple Stain MAX PO (G)
for HRP staining of human tissue with goat primary antibody
NIC-414162F
500 slides
2 x 17ml
$496
N-Histofine(R) Simple Stain AP (MULTI)
for AP staining human tissue with mouse or rabbit 1° antibody
NIC-414261F
170 slides
1 x 17ml
$443
N-Histofine(R) Simple Stain AP (MULTI)
for AP staining human tissue with mouse or rabbit 1° antibody
NIC-414262F
500 slides
2 x 17ml
$883

N-Histofine(R) Simple Stain AP(M)
for AP staining of human tissue with mouse primary antibody

NIC-414241F
170 slides
1 x 17ml
$443
N-Histofine(R) Simple Stain AP (M)
for AP staining of human tissue with mouse primary antibody
NIC-414242F
500 slides
2 x 17ml
$883
N-Histofine(R) Simple Stain AP (R)
for AP staining of human tissue with rabbit primary antibody
NIC-414251F
170 slides
1 x 17ml
$443
N-Histofine(R) Simple Stain AP (R)
for AP staining of human tissue with rabbit primary antibody
NIC-414252F

500 slides
2 x 17ml

$883




IMMUTEX Polystyrene Latex Particles  

IMMUTEX is a uniform-sized polystyrene latex particle for agglutination tests in clinical diagnostics. A variety of particle size and surface chemistry of IMMUTEX will meet your requirments to control sensitivity and dynamic range. IMMUTEX features a wide choice of particle size: 50nm to 1um, variety of surface chemistry, and are ready to use.

Item (click for product page) qty Cat. No. (click for datasheet) CBU Price
IMMUTEX P0001, 0.061μm 10 ML JSR-IMM-P0001 $310
IMMUTEX P2014, 0.075μm 10 ML JSR-IMM-P2014 $310
IMMUTEX P0011, 0.082μm 10 ML JSR-IMM-P0011 $310
IMMUTEX P2015, 0.086μm 10 ML JSR-IMM-P2015 $310
IMMUTEX P2116, 0.110μm 10 ML JSR-IMM-P2116 $310
IMMUTEX P2117, 0.121μm 10 ML JSR-IMM-P2117 $310
IMMUTEX P0112, 0.145μm 10 ML JSR-IMM-P0112 $310
IMMUTEX P2118, 0.153μm 10 ML JSR-IMM-P2118 $443
IMMUTEX P0113, 0.187μm 10 ML JSR-IMM-P0113 $443
IMMUTEX P2219, 0.220μm 10 ML JSR-IMM-P2219 $443
IMMUTEX P0307, 0.351μm 10 ML JSR-IMM-P0307 $443




Magnosphere™ Paramagnetic Particles  

Magnosphere™ products are a series of superparamagnetic microparticles for IVD and biotechnology research. Three types of beads are available with different surface chemistries (MB, MK and MS) to best meet your application needs. More info...


Features of Magnosphere™:

Uniform particle size
Core-shell structure
Good magnetic response
Good redispersablity
Diverse surface chemistry


Magnosphere surface chemistry and ligand coupling

Type 

Surface 

Non specific binding 

Surface functionality 

Ligand coupling 

MK

Hydrophobic 

 Low 

COOH 

Covalent coupling 

MB*

Hydrophobic 

Low

COOH 

Covalent coupling and/or physical adsorption 

MS

Hydrophilic 

Very Low 

COOH
Streptavidin

COOH: covalent coupling
Streptavidin: biotinylated ligand

*: MB is more hydrophobic than MK.

Item (click for product page) qty Cat. No. (click for data sheet) CBU Price
Magnosphere™ MB100/Calboxyl 5 ML JSR-MSP-B100-CA discontinued
Magnosphere™ MB200/Calboxyl 5 ML JSR-MSP-B200-CA $443
Magnosphere™ MC290/anti-EpCAM IgG 2 ML JSR-MSP-C290-AEP discontinued
Magnosphere™ MC290/anti-mouse IgG 2 ML JSR-MSP-C290-AMG discontinued
Magnosphere™ MC290/Streptavidin 2 ML JSR-MSP-C290-SA $443
Magnosphere™ MK230/Calboxyl 5 ML JSR-MSP-K230-CA discontinued
Magnosphere™ MS160/Carboxyl 4 ML JSR-MSP-S160-CA $530
Magnosphere™ MS160/Tosyl 4 ML JSR-MSP-S160-TS $530
Magnosphere™ MS300/Carboxyl 4 ML JSR-MSP-S300-CA $530
Magnosphere™ MS300/Low Carboxyl 4 ML JSR-MSP-S300-CAL $530
Magnosphere™ MS300/Protein A 2 ML JSR-MSP-S300-PA $443
Magnosphere™ MS300/Protein AG 2 ML JSR-MSP-S300-PAG discontinued
Magnosphere™ MS300/Papain 2 ML JSR-MSP-S300-PAP discontinued
Magnosphere™ MS300/Protein G 2 ML JSR-MSP-S300-PG $443
Magnosphere™ MS300/Protein L 2 ML JSR-MSP-S300-PL discontinued
Magnosphere™ MS300/Streptavidin 2 ML JSR-MSP-S300-SA $443
Magnosphere™ MS300/Tosyl 4 ML JSR-MSP-S300-TS $530
Magnosphere™ MX100/Calboxyl 5 ML JSR-MSP-X100-CA $443
Magnosphere™ MX200/Calboxyl 5 ML JSR-MSP-X200-CA $443


2D Silver Stain  
2D Silver Stain II Reagent Set
The finishing touch.

Even first time users can enjoy high sensitivity detection in as little as one hour with Cosmo's 2D-Silver Stain II Kit. 50-100 times more sensitive than CBB or ethidium bromide for protein or DNA detection, respectively. Easy to use kit produces even staining, low background, high contrast bands. Use for protein or DNA separated by PAGE or SDS-PAGE. Safe. No heavy metals except silver.
silver stain
 
   
Item
Cat. No
Quantity
Price
2D-Silver Stain II Reagent Kit silverstain
DCB-423413
1 set
$100

 

NOF Block  
Assay Blocking Reagents, 100% animal free synthetic polymer. 

Blocking reagents offer excellent performance, stability, and minimal lot to lot variation. NB4025 is especially efficient for preventing non-specific binding of Ig in human sera.

Also, based on similar polymers: enzyme stabilizers for  Alkaline Phosphatase and Peroxidase-linked assays.

image
 
   
Item (click for datasheet)
Cat. No
(click for web product page)
Quantity
Price
250 ml
$ 134
250 ml
$ 134
250 ml
$ 134

 

NOF Stabilizer  

100% animal free synthetic polymer.

Blocking reagents offer excellent performance, stability, and minimal lot to lot variation. NB4025 is especially efficient for preventing non-specific binding of Ig in human sera.

Also, based on similar polymers: enzyme stabilizers for Alkaline Phosphatase and Peroxidase-linked assays.

 
   
Item (click for datasheet)
Cat. No
(click for web product page)
Quantity
Price
Peroxidase Stabilizer ST2010 (25x)
100 ml
$22
ALP Stabilizer ST3010 (25x)
100 ml
$222
Phosphatase Stabilizer ST4010 (25x)
100 ml
$222



Multipurpose Incubation Chamber  
Ideal for any slide-based application requiring humid environment. Another Japan favorite. Weighty acrylic construction. Close fitting lid with wide rubber gasket prevents evaporation. Removable glass rods elevate samples. Use with Absorbent black paper for maintaing humid environment and high-contrast viewing. Much more than just a box, this is indeed a chamber. In clear, or orange for UV sensitive applications.
 
   
Item
Cat. No
Quantity
Price
Incubation Chamber, Small Cool Grey
KMB-10CG
1 chamber
$112
Incubation Chamber, Small Orange
KMB-10DO
1 chamber
$112
Incubation Chamber, Large, Grey
KMB-20CG
1chamber
$166
Incubation Chamber, Large Orange
KMB-20DO
1 chamber
$166
Glass rod replacement set for models 10CG and 10DO
KMB-GR10
2 rods with endcaps
$12
Glass rod replacement set for models 20CG and 20DO
KMB-GR20
2 rods with endcaps
$18
Black filter pads for all models
KMB-ICS
box of 50 sheets
$23



Unique Fluolid Fluorescent Dye Conjugation Kits for Oligoamines and Proteins

Fluorescent dye set with unique performance characteristics and labelling efficiency.

Fluolid dyes, for labeling of protein or oligo amines, feature high quantum yield in the solid state, no photo-bleaching, high stability towards light, temperature and pH, high incorporation rates, and very large Stoke's shifts.


 
   
Item
Cat. No
Quantity
Price
Fluolid-W Orange 600 Protein Labeling Kit
ISU-IST004
1 KIT
$662
Fluolid-W Yellow 540 Protein Labeling Kit
ISU-IST005
1 KIT
$662
Fluolid-W Green 520 Protein Labeling Kit
ISU-IST006
1 KIT
$662
Fluolid-W Orange 600 Oligonucleotide Amine Labeling Kit
ISU-IST001
1 KIT
$662
Fluolid-W Green 520 Oligonucleotide Amine Labeling Kit
ISU-IST003
1 KIT
$662
Fluolid-W Orange 600 Succeinimidyl Ester
ISU-ISTPW001-W
1 MG
$774
Fluolid-W Yellow 540 Succeinimidyl Ester
ISU-ISTPW002-W
1 MG
$774
Fluolid-W Green 520 Succeinimidyl Ester
ISU-ISTPW003-W
1 MG
$774
Fluolid-W Protein Labeling Trial Kit
ISU-ISTOYG
1Set
$662

 

PAP Pen Super Liquid Blocker  
This pen is designed to provide a water repellant barrier when a circle is drawn around a specimen/section. This barrier retains antisera within the defined area and ensures that only the amount of antibody needed for sufficient reaction is used, thus reducing waste. Multiple sections, separated by individual PAP Pen barriers, can be applied to the same slide and easily compared. 
pap pen
 
   
Item (click for product page
Cat. No (click for datasheet)
Quantity
Price
1 pen
$34
DAI-PAP-S 1 pen $52

 

Tissue Capture Pen  
The Tissue Capture Pen improves section attachment to glass slides during immunohistochemical staining. It creates a sticky surface on the glass slide ideally suited for paraffin or frozen section attachment. The Tissue Capture Pen greatly improves section adherence throughout long immunostaining protocols. It can be used in conjunction with the Super Pap Pen Liquid Blocker (#DAI-PAP-S) or the Mini Pap Pen Liquid Blocker (#DAI-PAP-S-M) which reduce the amount of antibody needed during labeling.
Tissue Capture
 
   
Item (click for product page)
Cat. No (click for datasheet)
Quantity
CBU Price
1 pen
$62

 

Tube Checker (solvent-proof marker)  
The Tube Checker' pen enable you to write on paper, plastic, glass and metal. The writings are waterproof after being dried and will not be blurred with water. After drying, written parts become solvent proof against organic solvent mainly used in the lab such as ethanol, xylene and chloroform.
Tube Checker
 
   
Item (click for product page)
Cat. No (click for datasheet)
qty
CBU Price
5 pen set
$34


Hybri-Bag  
Heat-sealable bags for hybridization and detection of blots. Available in three formats: Soft, Hard, and Hard with 1cm Grid. Hard Hybri-Bags are autoclavable. Can tolerate extremes of temperature (-80C to +80C). Dimensions: 200mm x 300mm. Reasonably priced.
 
   
Item
Cat. No
Quantity
Price
Hybri-Bag Hard (1cm grid)
SE-S-1002-EX
50 sheets
$49
Hybri-Bag Soft
SE-S-1021-EX
50 sheets
$49
Hybri-Bag Hard
SE-S-1001-EX
50 sheets
$49

 

Easy-WESTERN II  
Easy-WESTERN II is developed basing on " MAD" (multi-purpose antibody detecting) technology. The main componet of MAD is protein particles which binds to the Fc region of antibodies. Each particle has ~100 Fc-binding proteins and labeled with ~ 50 molecules of HRP. Thus Easy-WESTERN II provides simple, high sensitivity, and quick detection of primary antibodies without using secondary antibodies.
 
   
Item
Cat. No
Quantity
Price
50 assays
$331
50 assays
$364
50 assays
$387
50 assays
$367

Antibodies to Immunoglobulins (Human, Mouse, Rat)  
Reactivity
Species
Host
Clone
Antibody Subclass
Catalog Number
anti IgA
Human
Mouse
A2A13
IgG1
anti-IgA
Human
Mouse
IgA-13
IgG2b
anti-IgA, secretory
Human
Mouse
5831
IgG1
anti-IgA1
Human
Mouse
7303B
IgG1
anti-IgA2
Human
Mouse
7311A
IgG1
anti-IgD
Human
Mouse
IgD-10
IgG1
anti-IgE
Human
Mouse
23F4
IgG2a, kappa
anti-IgE
Human
Mouse
29D10
IgG1, kappa
anti-IgE
Human
Mouse
IgE-4
IgG1
anti-IgE
Human
Mouse
6H413
IgG1
anti-IgE, HRP
peroxidase conjugated
Human
Mouse
10H3-3
IgG1
anti-IgG
Human
Mouse
IgG-B-22
IgG2a
anti-IgG
Human
Mouse
IgG-19
IgG1
anti-IgG
Human
Mouse
1B9
IgM
anti-IgG
Human
Mouse
1F913
IgG2a
anti-IgG, peroxidase conjugated
Human
Mouse
1F913
IgG2a
anti-IgG3
Human
Mouse
5H92a
IgG2b
anti-IgG3, HRP
Human
Mouse
5H9-2a
IgG2b
anti-IgG4
Human
Mouse
5C3
IgG1
anti-IgG4, HRP
Human
Mouse
5C3
IgG1
anti-IgM
Human
Mouse
IgM-49
IgG1
anti-IgM
Human
Mouse
2C12-3
IgG2b
anti-IgM, HRP
Human
Mouse
2C123
IgG2b
anti-Kappa Light Chain
Human
Mouse
KL-101
IgG1?
NBT-MKL-101
anti-Kappa Light Chain
Human
Mouse
KL-102
IgG2a?
NBT-MKL-102
anti-Kappa Light Chain
Human
Mouse
2G5-14
IgG1
anti-Kappa Light Chain, HRP
Human
Mouse
2G5-14
IgG1
anti-Lambda Light Chain
Human
Mouse
A2A5
IgG2a
YMS-7590
anti-Lambda Light Chain, HRP
Human
Mouse
A2A5
IgG2a
YMS-7640
anti-IgE
Mouse
Rat
6HD5
IgG2a, kappa
anti-IgE, Biotin
Mouse
Rat
HMK-12
IgG2a,kappa
YMS-7617
anti-IgE
Rat
Mouse
AREB10
IgG2b
anti-IgE, HRP
Rat
Mouse
AREB6
IgG1
YMS-7593
anti-IgE, HRP
Rat
Mouse
AREB7
IgG1
anti-Kappa Light Chain
Rat
Mouse
M21
IgG1

 

Luciferase FM Assay Kits  
The determination of ATP concentration in unknown samples by bioluminescence using ATP-dependent luciferase enzymes is a well-established method. Luciferase FM is a genetically modified variant of native North American firefly (photinus pyralis) luciferase generating a luminescence intensity approximately 10 times greater than wild-type enzyme. The increased brightness of Luciferase FM significantly extends the limits of ATP detection in standard assays.

CSR-LUC-E01:

10 x 1 mg Luciferase FM
enzyme, lyophilized
(1-10 x 1016 Relative Light
Units / mg protein.)

CSR-LUC-E02:

10 x kit: 2 x 5 ml Luciferin FM reagent premix, lyophilized. 30 ml ATP-free sterile water, ready to use.
Item
Cat. No
Quantity
Price
CSR-LUC-E01
10*1MG
$5,071
CSR-LUC-E02
10*80TEST
$6,174

V161018SS

 

 

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