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what's up.doc, No. 33,"Detection
Reagents"
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Tools and Reagents for Optimizing Assay
Development, Immunodetection
and Molecular Biology
Procedures
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New Fluorescent Dyes |
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IHC Detection
Kits |
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IST Fluolid - Fluorescent
dyes with unique performance characteristics and labelling
efficiency.
Fluolid
dyes, for labeling of protein or oligoamines, feature high quantum yield in the
solid state, no photo-bleaching, high stability towards light,
temperature and pH, high incorporation rates, and very large
Stoke's shifts.
Ex/Em maxima: Fluolid-W
Orange 440/602 Fluolid-W Yellow 410/541 Fluolid-W
Green 395/522 |
IST Fluolid Unique Fluorescent Dye
Set |

Mouse spleen detected with
N-Histofine® Simple Stain Max PO. |
N-Histofine® MAX PO and Simple Stain Detection Kits
Patented polymer technology ensures strong signal amplification and low
background for high sensitivity staining. Uneffected
by endogenous biotin in tissue. Histofine
kits are available for use with Human,
Mouse and Rat tissue and mouse, rabbit, and goat primary
antibodies.
Check our
website for complete product listing and
pricing. |
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Antibody Rxn Enhancer for
Blotting and Assays |
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Antibody Rxn
Enhancer for Tissue Staining |
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Can Get™Signal Immunoreaction Signal
Enhancer. Improves antibody
performance.
Simply use Can Get as
antibody diluent for Westerns, ELISAs, and dot blots for dramtically
increased s/n ratio in many systems. Compatible with
colorimetric, chemiluminescent, and fluorescent detection methods. Enzyme
labeled antibodies are not disturbed. Can Get Enhancer Trial set
includes one solution optimized for 1° abs and one solution optimized
for 2° abs.
TYB-NKB-101T, Can Get Signal Immunoreaction
Enhancer Trial Set |

Improved detection of phosphorylated Akt with
insulin stimulated bovine cells. |

Tricolor merged image using Can
Get Signal®
Immunostain solutions. |
Can Get Signal® Immunostain Signal Enhancer.
Improves antibody performance in IHC and ICC.
Optimized for cell staining,
Can Get Immunostain Enhancer increases s/n ratio and decreases
non-specific background. Fully compatible with enzyme and fluorescent
dye-labeled antibodies. Use for paraffin embedded or frozen sections. Try “A” type
and “B” type (in Starter Set) included in Starter Set to find which
works best in your system.
TYB-NKB-401, Can Get Signal Immunostain
Enhancer Starter Kit |
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Improved
Hybridization |
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Gold Medal
in Silver Staining |
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PerfectHyb® hybridization
solution
- ready to use
A single solution containing
a proprietary hybridization enhancer, PerfectHyb® is ideal for
detecting low copy number genes. Optimized for performance in Northerns and Southerns,
including non-radioactive methods. Fast, convenient hybridization is complete in
1-2 hrs. No salmon sperm DNA required. Hybridize and wash at the same
temperature.
TYB-HYB-101, PerfectHyb® Hybridization Solution, 250ml, |

Northern Blot detection of transferrin receptor in
HeLa cells. 1:
PerfectHyb® , 2
hr
2: company A, 2 hr 3: company B, 2
hr 4: conventional methods, 16 hr |

Fermentas SM1811 protein ladder from 4x to
1024x dilution, 3 ul each lane (not greater than 0.6 picograms
protein/band at 1024x). |
2D Silver Stain II
Kit
The finishing
touch.
Even first time users can
enjoy high sensitivity detection in as little as one hour with Cosmo's
2D-Silver Stain II Kit. 50-100 times more sensitive than Coumassie Blue or ethidium
bromide for protein or DNA detection, respectively. Easy to use kit
produces even staining, low background, and high contrast bands. Use
for protein or DNA separated by PAGE or SDS-PAGE. Safe. No heavy metals
except silver.
DCB-423413, 2D-Silver Stain II
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| Polymer-Based Assay Blockers And Enzyme
Stabilizers |
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Slide Incubation
Chamber |
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Assay Blocking Reagents , 100% animal free synthetic polymer.
These
unique blocking reagents offer excellent performance, stability, and minimal lot-to-lot
variation. NB4025 is especially efficient to prevent non-specific binding of Ig
in human sera.B ased on similar synthetic
polymers, Peroxidase and Phosphatase Stabilizer Reagents also
offer excellent performance.
Blocking Reagent NB-2025 (25x) Blocking Reagent NB-3025
(25x) Blocking Reagent NB-4025(25x)
250 ml,
(each)
Perox. Stabilizer ST2010
(25x) Phosph. Stabilizer ST3010 (25x) Phosph. Stabilizer
ST4010 (25x)
100 ml, (each) |
 Stability to detergent: Blocks better
than casein in presence of Tween.
 % recovery of peroxidase activity
following dilution in ST2010 (0.1mg/ml final peroxidase
concentration).
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Much more than just a box. |
Multipurpose Incubation Chamber
Ideal for any
slide-based application requiring humidified environment.
A favorite in Japan. Weighty acrylic
construction. Close fitting lid with wide rubber gasket prevents
evaporation. Removable glass rods elevate samples. Absorbent black bottom pad for moist
keeping and high-contrast viewing. Available in cool grey, and dark orange for UV sensitive
applications.
Incubation Chamber, small for 10
slides.
Incubation Chamber, large for 20
slides. |
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When Only The Best Gels Will Do |
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Heat Sealable
Bags |
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Multigel® II Mini, Precast PAGE
Gels A true favorite in Japan, available
worldwide only from Cosmo Bio. Multigel II’s improved
Laemmli formulation and new advanced comb design produce sharp, high
resolution bands from top to bottom. Available in fixed percentage,
wide-gradient, and narrow gradient formats. A great choice for general research
or commercial quality control.
Multigel II Mini plate size: 100 x 100 x 3.1 mm
Multigel II Mini gel
Size: 85 x 90 x 0.9 mm
Certain
formulations also available in larger format |

4-20% Multigel II Mini Precast PAGE Gel showing Fermentas
SM0671 (odd lanes) and SM1811 protein ladders (even
lanes).
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Choose from Soft, Hard, or Hard Grid
format.
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Hybri-Bags ideal
for hybridization of
membrane blots.
New to Cosmo Bio, Hybri-Bags
are easy to seal, strong, tolerate -80C to +80C, powder-free, and
reasonably priced. A
vailable with polyethylene (soft) or polypropylene (hard)
interiors. Hard Hybri-bags are
autoclavable.
SE-S-1002-EX
Hybri-Bag, Hard (1cm Grid) SE-S-1001-EX Hybri-Bag,
Hard SE-S-1021-EX Hybri-Bag, Soft
| Contacts In the USA, contact Cosmo Bio USA (Carlsbad,CA), info@cosmobiousa.com,
1-866-921-3686. For all other countries, contact Cosmo Bio Co., Ltd .
(Tokyo),export@cosmobio.co.jp
, +(81)-3-5632-9617).
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About Cosmo Bio
Cosmo Bio brings you select reagents and
small instruments for life science research from Japan. With well over
1,000 products from more than 40 Japanese manufacturers and academic labs,
the Cosmo Bio catalog conveniently consolidates a wide range of unique and
routine research tools. Our catalog includes a large number of
antibodies, ELISA kits, and other products based
on immunodetection. But also a lot more. Many products from
Cosmo Bio have previously been unavailable commercially or outside of
Japan.
For over 25 years, Cosmo Bio has been
fully committed to exceeding customer expectations by
providing......quality products...and the highest standards of customer
care and support.
Orders and
Inquiries Except in the USA, orders ship directly from
Japan. USA customers: please contact Cosmo Bio
USA in Carlsbad, CA (San
Diego County). |
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