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**Special Offers to Cosmo Bio
USA Customers**
25% off Histone H3
Monoclonals
until June 30,
2010
20% off Unique Cell/Tissue Culture
Tools
until June 30,
2010
Inventory Clearance Specials
While
supplies
last
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UV
Radiation
DNA
Damage
Monoclonals
Prolonged exposure to solar UV
radiation may result in acute and chronic health effects
on the skin, eye, and immune system. These harmful
effects are suggested to relate to DNA damage. The major types
of DNA damage induced by UV radiation are cyclobutane
pyrimidine dimers (CPDs), 6-4 photoproducts (6-4PPs), and
Dewar photoproducts (DewarPPs). Cosmo Bio offers well
characterized monoclonal antibodies specific for these DNA
lesions.
View
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Ubiquitination
Anti Usp11
Polyclonal
Usp11 (ubiquitin specific
peptidase 11) contains a cys box, his box, asp and krf
domains which are highly conserved in many ubiquitin specific
proteases. Usp11 is found in various tissues and is primarily
localized in the nucleus of non-dividing cells. Usp11 binds
specifically to RanBPM which is required for correct
nucleation of microtubles and inhibits its ubiquitination and
degradation.
View
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Aquaporin
Transport
Anti
AQP1
Aquaporin 1 is a 28kDa integral
protein that is abundant in erythrocytes and renal tubules.
AQP1 is also expressed by the choroid plexus and various other
tissues. It forms a water specific channel that provides the
plasma membranes of red cells and kidney proximal tubules with
high permeability to water, thereby permitting water to move
in the direction of an osmotic gradient.
View
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Thombosis
Research
TpP
ELISA
Thombus
precursor protein (TpP) which measures soluble fibrin, is a
marker of active thrombosis. After thrombin cleaves
fibrinopeptide A and B from fibrinogen, desAABB fibrin
monomers are formed. These monomers polymerize into soluble
TpP fibrin polymers, which serve as the immediate precursors
to insoluble fibrin.
View
Website
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Oxidative
Stress
Potenital Antioxidant
Assay
Oxidative stress
plays an important role in various diseases and aging. For
accurate assessment of oxidative stress, measurement of ROS,
oxidative damage, and antioxidant activity may be essential.
In the PAO assay kit, an easy and convenient method to measure
antioxidant capacity is provided. Applications include:
serum, food and beverage samples.
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Glycobiology
Hyaluronic Acid
oligos
Hyaluronic acid (HA) is constructed
from repeating disaccharide units. HA exists in alsmost all
vertebrates and distributed in all parts of the body. Recently
low molecular weight HA oligos have shown to be involved
in the induction of NO and MMPs in
chondrocytes.
View Website
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Glycation
Research
Anti AGEs
The
products of the nonenzymatic glycation and oxidation of
proteins, lipids, and nucleic acids, advanced glycation
end-products (AGEs), accumulate in various pathological
conditions, such as diabetes, inflammation, renal failure, and
aging. This antibody, clone 6D12, idenifies AGEs modified
proteins in human tissues in IHC, Western blot, and ELISA
applications.
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Glycation
Research
Glucose-derived AGEs
ELISA
As
a follow up to results obtained with anti AGEs antibodies,
this assay was developed to detect glucose-derived AGEs in
samples.
View
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Totally Unique Transfection
Alternative
GenomOne-Neo
Utilizes the membrane
fusion properties of HVJ (Sendai virus) envelope
to transfect cells with DNA, RNA or proteins. Over
100 references in vivo and in vitro. Great for
siRNA.
View Website
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About
Cosmo Bio
Cosmo Bio USA is the exclusive US distributor for Cosmo Bio Co., Ltd.
(Tokyo), bringing you select
reagents and small instruments for life science research from
Japan. With well over 1,000 products from more than 40 Japanese
manufacturers and academic labs, Cosmo Bio conveniently consolidates a
wide range of routine and highly unique biotools including over 1,000
antibodies, ELISA and assay kits, and much more. Many products from Cosmo
Bio have previously been unavailable commercially or outside of
Japan.
For over 25 years, Cosmo Bio has been fully
committed to exceeding customer expectations by providing quality
products and the highest standards of customer care and
support.
Orders and Inquiries
USA orders ship directly from Cosmo Bio USA ,
Inc in
Carlsbad, CA (San Diego County). |
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This message was sent
from Cosmo Bio USA, Inc., 2792 Loker Ave W, Suite 101, Carlsbad, CA
92010, USA.
1-760-431-4600 phone / 1-760-431-4604 fax /
1-866-921-3686 toll free
info@cosmobiousa.com
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