What's up.doc,  No. 132  "Product Showcase 15" 
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**Special Offers to Cosmo Bio Customers**

*PURESYSTEM: Cell-free Protein Synthesis System

15% Discount Until December 28, 2009

*
Human Collagen Type 1 ELISA kit
Save 37%  Until December 28, 2009

*
Inventory Clearance Specials for USA Customers only
While supplies last

 Recombinant Protein Synthesis 

PURESYSTEM 

 

Reconstituted from over 30 HIS-tagged components, and purified E.coli ribosomes, the PURESYSTEM line of cell-free transcription/translation kits lets you purify native or tagged proteins in just 2-3 hours by negative purification using metal affinity chromatography. Lysate free PURESYSTEM virtually eliminates degradation by nucleases and proteases. Kits for synthesis under reducing and oxidizing conditions also available. 15% off until Dec. 28, 2009.
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Lipid Research 

Anti FFAR2
 
 
The short-chain fatty acid receptor FFAR2 (free-fatty acid receptor 2; GPR43) is a G-protein coupled receptor for short chain fatty acids such as acetate and propionate. FFAR2 is abundant in leukocytes and adipose tissue and appears to be expressed by peptide YY (PYY)-immunoreactive enteroendocrine L cells in human large intestine. FFAR2 activation can activate Gi and Gq. In FFAR2 deficient mice, FFAR2 activation in adipocytes resulted in inhibition of lipolysis and a reduction of plasma free fatty acids. This mouse monoclonal antibody is reactive with human and rat FFAR and tested for IHC and ELISA applications.
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Autophagy Research

Anti LC3


Autophagy induction in mammalian cells induces LC3 (mirotubules-associated light chain 3; homology of yeast Atg8) conjugation to phosphatidylethanolamine and subsequent targeting to autophagic membranes. A general correlation between the amount of membrane-bound LC3 and the number of cellular autophagosomes has led to the use of LC3 expression levels as an index of autophagy (however, see PMID:17387262). Use clone LC3No6 to detect both unprocessed and membrane bound LC3 in human and mouse cells. 
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Atherosclerosis Research

Anti 7-ketocholesterol 


Visualize 7-ketocholesterol in frozed tissue with this highly specific mouse monoclonal. 7-ketocholesterol (7KC), a cholesterol oxidation product, has received attention because of its presence in human atherosclerotic plaques and its atherogenic properties. Anti-7-KC shows virtually no reactivity with related molecules including TriOL, 7betaOH, CHOL, and others.
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Endocrine Research

CRH ELISA

Corticotropin Releasing Hormone (CRH)  is a 41 aa peptide hormone produced by the hypothalamus that stimulates the release of corticotropin by the anterior pituitary. CRH levels may rise or fall under various physiological conditions including during pregnancy. Measure human CRH in biological fluids with a dynamic range of 0.16ng/ml-10ng/ml. Sandwich assay format with colorimetric detection utilizing TMB peroxidase substrate read at 450nm.
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Food Safety    

Immunochromato Salmonella
     


The self-contained NH Immunochromato immunochromatography cassette is for the rapid, semi-quantitative detection of salmonella antibodes in food samples. Simply apply your samples and read your results. NH Immunochromato kits are also available for a variety of other food born pathogens and common allergens.
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Cell Culture
 
M-Stars Medium



Complete culture medium optimized for epithelial cells. Excellent for primary corneal epithelial and oral mucosaepithelial. M-Stars is ready to use right out of the bottle, complete with growth factors, fetal bovine serum, and antibiotics.
DISCONTINUED

Phospholipid binding 

Annexin I ELISA





Uncover the functions of annexin family members with ELISA assay kits to measure annexins in culture supernates, serum, and other biological fluids. The Annexin I ELISA, manufactured by Cusabio, features high specificity and detection between 15-1000ng/ml in a sandwich assay format utilizing peroxidase conjugated antibody and TMB as peroxidase substrate. Kits are also available for Annexins 2-4, 6 & 7 .
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Totally Unique Transfection Alternative  

GenomOne-Neo


Utilizes the membrane fusion properties of HVJ (Sendai virus) envelope to transfect cells with DNA, RNA or proteins. Over 100 references in vivo and in vitro. Great for  siRNA.   
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About Cosmo Bio

Cosmo Bio USA is the exclusive US distributor for Cosmo Bio Co., Ltd. (Tokyo), bringing you select reagents and small instruments for life science research from Japan. With well over 1,000 products from more than 40 Japanese manufacturers and academic labs, Cosmo Bio conveniently consolidates a wide range of routine and highly unique biotools including over 1,000 antibodies, ELISA and assay kits, and much more. Many products from Cosmo Bio have previously been unavailable commercially or outside of Japan. 

For over 25 years, Cosmo Bio has been fully committed to exceeding customer expectations by providing quality products and the highest standards of customer care and support. 

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