What's up.doc,  No. 121  "Product Showcase 12" 
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**Special Offers to Cosmo Bio Customers**

*PURESYSTEM: Cell-free Protein Synthesis System

15% Discount Until December 28, 2009

*
Human Collagen Type 1 ELISA kit
Save 37%  Until December 28, 2009

*
Inventory Clearance Specials for USA Customers only
While supplies last

 DNA Repair

Anti Rad18

 
Rad18 ubiquitin ligase interacts with Rad6 ubiquitin conjugating enzyme to promote translesion synthesis during post-replication repair of radiation damaged DNA. A recent study suggests that RAD18 promotes 53BP1-directed DSB repair by enhancing retention of 53BP1 (PMID 19228710). This antibody can be used to further define the role of Rad18 in human DNA repair.
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Bone Research

Anti Matrix Gla Protein
 
 
Matrix Gla Protein (MGP) appears to act as a calcification inhibitor. MGP binds calcium through it's five gamma-carboxylated glutamic acid (Gla) residues. Though widely expressed, MGP accumulates significantly only in bone, cartilage, and dentin. Visualize MGP expression in mouse tissue by immunohistochemistry with this rabbit polyclonal antibody.
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Transcription Factor

Anti Twist



Monoclonal anti-Twist (clone Twist2C1a) is a versatile performer for use in human, mouse and rat systems and recommended for blotting, flow cytometry, and immunohistochemical applications. As a basic helix-loop-helix transcription factor, Twist has been implicated in cell lineage determination and differentiation. Twist mutations have been noticed in patients with Saethre-Chotzen syndrome, an autosomal dominant disorder characterized by cranial-facial dismorphisms or other structural abnormalities.
 
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Protein Folding

 HSP90 Antibodies 




 Heat Shock Protein 90 (HSP90) is one of the most abundant proteins in all cell types with critical functions in protein folding, cell signalling, and other processes. Distinguish between human HSP90-alpha and HSP90-beta isoforms or measure total HSP90-alpha/beta using combinations of these seven well defined monoclonal antibodies.
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Endocrine Research

Glucagon Products




 
Specifically measure pancreatic glucagon in human, rat, or mouse plasma with this highly advantageous kit utilizing antibody to the Glucagon C-terminal region. Also note Cosmo offers a range of related ELISA kits and antibodies to GLP-1, GLP-2, and Glicentin.
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Collagen Research   

Anti Collagen II Ab Assays
     


Anti-collagen Type II antibodies are effectors of inflamation in rheumatoid arthritis models. Their presence in serum is indicative of arthritis onset. Rheumera ELISA kits are available for the sensitive detection of anti-Collagen Type II antibodies in human, mouse, or rat serum.
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Culture Substrate
 

Chitosan Nanofiber Matrices



Cultureware coated with spatially aligned Chitosan Nanofiber--a new advanced, electrospun preparation from crab shell--is an excellent substrate for many types of adhesive cells and offers advantages to poly-L-lysine or collagen coatings.
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CpG Methylation 

Anti Dnmt1



 DNA methyltransferase (cytosine-5) 1 (Dnmt1) is a key enzyme for maintenance of genomic CpG methylation patterns and has critical functions in embryogenesis. Raised against recombinant human Dnmt1 (aa1-248), this multi-talented antibody excels at binding native Dnmt1 and can be used for immunoprecipitation, western blotting, and immunofluorescence.
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Totally Unique Transfection Alternative  

GenomOne-Neo


Utilizes the membrane fusion properties of HVJ (Sendai virus) envelope to transfect cells with DNA, RNA or proteins. Over 100 references in vivo and in vitro. Great for  siRNA.   
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About Cosmo Bio

Cosmo Bio USA is the exclusive US distributor for Cosmo Bio Co., Ltd. (Tokyo), bringing you select reagents and small instruments for life science research from Japan. With well over 1,000 products from more than 40 Japanese manufacturers and academic labs, Cosmo Bio conveniently consolidates a wide range of routine and highly unique biotools including over 1,000 antibodies, ELISA and assay kits, and much more. Many products from Cosmo Bio have previously been unavailable commercially or outside of Japan. 

For over 25 years, Cosmo Bio has been fully committed to exceeding customer expectations by providing quality products and the highest standards of customer care and support. 

Orders and Inquiries
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