What's up.doc,  No. 118   "Product Showcase 11" 
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**Special Offers to Cosmo Bio USA Customers**
*PURESYSTEM: Cell-free Protein Synthesis System

Buy 1 kit from This List, get 1 mini kit (Classic, S-S, or Advance) free.
Until September 30, 2009


*GenomONE HVJ Envelope Transfection and Cell Fusion kits

Save 15% on Neo and CF kits
Until September 30, 2009


*
Inventory Clearance Specials for USA Customers only
While supplies last

 Neurodegenerative Disease 

Phospho-TDP-43 Antibodies


 


Powerful new antibodies for probing the role of phosphorylation in the pathology of cytoplasmic and nuclear inclusions associated with ALS and FTLD-U disease, as described recently in Annals of Neurology (PMID:l8546284). TDP-43 is the major protein in ubiquitinated ALS and FTLD-U inclusions. 
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Liver Disease

Anti Adenosine Deaminase 2
 
  

Relatively little is known regarding the function of the ADA2 isoform of the purine metabolic enzyme adenosine deaminase. ADA1 is the major intracellular isoform while ADA2 accounts for 70% of human plasma ADA. AN increase in plasma ADA2 activity has been noticed in hepatitis and hepatic cirrhosis. Macrophage have been identified as a source of plasma ADA2 during inflammation.
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Alport's Syndrome

Fluorochrome Conjugated Antibodies



              
Alport's Syndrome patients fail to form alpha-5 type IV collagen fibers due to inherited genetic mutations. The absence of alpha-5 type IV collagen fibers in liver tissue can be determined by staining with the two monoclonal antibodies included in this set: FITC-conjugated anti-alpha5(IV) and Texas Red anti-alpha2(IV). 
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Cancer Research

 Human Tumor Marker Antibodies 



 Alfa-fetoprotein (AFP), carcinoembrionic antigen (CEA), prostatic acid phosphatase(PAP), and ferritin are "classical" tumor markers whose presence in blood, urine, or other fluids have been evaluated for utility in early diagnosis determination, predicting responsiveness to cancer therapies, patient surveillance after initial therapy, and monitoring response to therapy in advanced cancers.
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Endocrine Research

GLP-1 ELISA




 The intestinal hormone GLP-1, derived form proglucagon, is a potent insulin secretagogue and effective for reducing hyperglycemia due to type 2 diabetes. This kit is a sensitive immunoassay for quantitating GLP-1 amide in 30ul of rat, mouse, or human plasma. In this assay, GLP-1 in samples inhibits the maximal binding of biotin-labeled GLP-1 to an anti-GLP-1 antibody. Kits specific for GLP-2 and other endocrine hormones are also available.
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Transcription Factor Binding  

NF-kB Decoy Kits
    
 

NF-kB decoy oligonucleotides suppress transcription of NF-kB responsive genes by preventing the binding of NF-kB to natural genomic binding sites. The decoy oligonucleotides in these kits are available in linear form, or in ribbon (circular) or phosphorothioate forms for increased nuclease resistance. Control oligonucleotides with scrambled nucleotide sequence are included. For Research Use Only.
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Food Safety
 

NH Immunochromatato 0157





 Small, convenient, and totally self-contained immunochromatography unit for rapid, sensitive, and reproducible semi-quantitative detection of E. coli 0157 antigens in samples. NH Immunochromata kits are also available for a host of other food borne pathogens and common allergens.
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Cell Culture Substrate 

Mebiol Gel



 Highly unique thermo-reversible polymer for 3-D cell / tissue culture. Useful as a substrate for ES cells, chondrocytes, cancer cells, etc. Mebiol Gel is a liquid at low temperature, and becomes a gel at high temperature.

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Totally Unique Transfection Alternative  

GenomOne-Neo



Utilizes the membrane fusion properties of HVJ (Sendai virus) envelope to transfect cells with DNA, RNA or proteins. Over 100 references in vivo and in vitro. Great for  siRNA. 
  
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About Cosmo Bio

Cosmo Bio USA is the exclusive US distributor for Cosmo Bio Co., Ltd. (Tokyo), bringing you select reagents and small instruments for life science research from Japan. With well over 1,000 products from more than 40 Japanese manufacturers and academic labs, Cosmo Bio conveniently consolidates a wide range of routine and highly unique biotools including over 1,000 antibodies, ELISA and assay kits, and much more. Many products from Cosmo Bio have previously been unavailable commercially or outside of Japan. 

For over 25 years, Cosmo Bio has been fully committed to exceeding customer expectations by providing quality products and the highest standards of customer care and support. 

Orders and Inquiries
USA orders ship directly from
Cosmo Bio USA , Inc  in Carlsbad, CA (San Diego County). 

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