What's up.doc,  No. 101,  "Product Showcase 6"          Cosmo Bio Home                                            Products                                            New Products                             Order/Contact More Cool Biotools from Japan           Drosophila Research  Anti SSRP1 Antibody   SSRP1 and SPT16 are subunits of the FACT heterdimer which, among other reported properties, interacts with histones and facilitates nucleosome disassembly and transcription. This wellcharacterized polyclonal antibody, raised against recombinant Drosophila SSRP1, is qualified for Western blotting, immunostaining, immunoprecipitation, and chromatin immunoprecipitation (ChIP). View Website Proteasome Function Anti Rat Oazin       Oazin is a human homolog of rat antizyme inhibitor. Antizyme stabilizes ornithine decarboxylase, a key enzyme in polyamine biosynthesis. Oazin is also reported to play a role in proteasome-mediated degradation of proteins involved in cell proliferation, and recently in the regulation of centrosome homeostasis and oncogenesis. Raised against mouse oazin, but cross reactive with human, clone H12 is so far qualified for Western blotting and immunocytochemistry. View Website Allergy Research Anti FceR1 alpha (CRA1)               IgE binds directly to the FceR1 alpha subunit of the tetrameric high affinity IgE receptor. This versitile, widely cited monoclonal antibody is available unconjugated or as biotin and FITC conjugates and recommended for Western blotting, IHC, and flow cytometry.  View Website Oxidative Stress  Protein Carbonyls Western kit Protein carbonyls are often used as a marker of oxidative stress. This kit avoids the earlier problem of altered electrophoretic mobility due to DNP-derivitization of carbonyls prior to membrane transfer by shifting the derivitization step to membrane transfered proteins. View Website          Endocrine Research Rat Leptin ELISA Leptin is a 16 kDa circulating adipokine acting primarily in the hypothalamus to decrease appetite and increase energy expenditure. This sandwich ELISA, designed specifically for rat leptin, combines easy sample prep (plasma, serum, culture supernatant) with reliable quantitation, high specificity, and freedom from interfering substances. View Website Polyamine Detection  Urinary Diacetylspermine ELISA   Convenient assay designed for human urine samples. Diacetylspermine (DiAcSpm) in samples inhibits the maximal binding of DiAcSpm antibody to immobilized DiAcSpm. Antibody bound to immobilized DiAcSpm is then quantitated with peroxidase-labeled anti IgG and peroxidase substrate OPD. A kit for Urinary diacetylspermidine is also available. View Website RNA Transcription Thermo T7 RNA Polymerase This modified T7 RNA polymerase allows for reactions at 50C and improved fidelity at 37C. Applilcations include: in vitro transcription, RNA probes, etc.  View Website RB Research   Anti RBP2/JARID1A A Jumonji family protein, RBP2/JARID1 is a specific Histone 3 K4 demethylase that regulates HOX gene expression and is required for normal development. Reactive with human and mouse. Detects endogenous protein in Western blots. View Website Totally Unique Transfection Alternative   GenomOne-Neo Utilizes the membrane fusion properties of HVJ (Sendai virus) envelope to transfect cells with DNA, RNA or proteins. Over 100 references in vivo and in vitro. Great for  siRNA.   View Website

About Cosmo Bio Cosmo Bio USA is the exclusive US distributor for Cosmo Bio Co., Ltd. (Tokyo), bringing you select reagents and small instruments for life science research from Japan. With well over 1,000 products from more than 40 Japanese manufacturers and academic labs, Cosmo Bio conveniently consolidates a wide range of routine and highly unique biotools including over 1,000 antibodies, ELISA and assay kits, and much more. Many products from Cosmo Bio have previously been unavailable commercially or outside of Japan.  For over 25 years, Cosmo Bio has been fully committed to exceeding customer expectations by providing quality products and the highest standards of customer care and support.  Orders and Inquiries USA orders ship directly from Cosmo Bio USA, Inc  in Carlsbad, CA (San Diego County).

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